2011年6月，南华大学认知与神经系统疾病研究所（简称南华大学神经科学研究所）在原生理学教研室的基础上成立，由胡弼教授任研究所学术委员会主任，唐小卿博士任研究所所长，田绍文博士任研究所副所长。
基本介绍
- 中文名：南华大学认知与神经系统疾病研究所
- 外文名：Institute of Cognition and Nervous System Diseases.USC
- 别称：南华大学神经科学研究所
- 通信地址：湖南省衡阳市常胜西路28号
简介
早在2003年，南华大学医学院生理学科就开展了一系列认知神经科学和神经变性病的研究，经近10年的不断探索，已成为湖南省内一支重要的神经科学研究队伍，是中国生理学会理事单位以及湖南省生理科学会副理事长单位。在不断创新与开拓过程中，本所形成了认知障碍性疾病和神经变性疾病两个研究水平省内领先的科研主攻方向。
研究方向
认知障碍性疾病
神经变性疾病
近年来发表的SCI文章
序号 | 第一作者/通讯作者* | 论文名称 | 刊物 | 年度 |
1 | 唐小卿 | A novel mechanism of formaldehyde neurotoxicity: inhibition of hydrogen sulfide generation by promoting overproduction of nitric oxide. | PLoS One | 2013 |
2 | 唐小卿 | Formaldehyde impairs learning and memory involving the disturbance of hydrogen sulfide generation in the hippocampus of rats | J Mol Neurosci. | 2013 |
3 | 唐小卿 | Role of Paraoxonase-1 in the Protection of Hydrogen Sulfide-Donating Sildenafil (ACS6) Against Homocysteine-Induced Neurotoxicity | J Mol Neurosci. | 2013 |
4 | 唐小卿 | Hydrogen sulfide prevents formaldehyde-induced neurotoxicity to PC12 cells by attenuation of mitochondrial dysfunction and pro-apoptotic potential. | Neurochem Int | 2012 |
5 | 唐小卿 | Involvement of K(ATP)/PI (3)K/AKT/Bcl-2 pathway in hydrogen sulfide-induced neuroprotection against the toxicity of 1-methy-4-phenylpyridinium ion. | J Mol Neurosci. | 2012 |
6 | 凌宏艳 | MiRNA-21 reverses high glucose and high insulin induced insulin resistance in 3T3-L1 adipocytes through targeting phosphatase and tensin homologue. | Experimental and Clinical Endocrinology & Diabetes. | 2012 |
7 | 凌宏艳/ 胡弼* | Arecoline improves vascular endothelial function in high fructose-fed rats via increased CSE expression and activation of KATP channels. | Acta Pharmacol Sinica. | 2012 |
8 | 凌宏艳 | The role of epigenetic regulation in diabetes and its complications | Prog Biochem Biophys. | 2012 |
9 | 顾洪丰 | Psychological stress, immune response and atherosclerosis | Atherosclerosis | 2012 |
10 | 唐小卿 | Inhibition of hydrogen sulfide generation contributes to 1-methy-4- phenylpyridinium ion-Induced neurotoxicity | Neurotoxicity Research | 2011 |
11 | 唐小卿 | Formaldehyde induces neurotoxicity to PC12 cells involving inhibition of paraoxonase-1 expression and activity | Clin Exp Pharmacol Physiol. | 2011 |
12 | 唐小卿 | Inhibition of endogenous hydrogen sulfide generation is associated with homocysteine-induced neurotoxicity: role of ERK1/2 activation | J Mol Neurosci | 2011 |
13 | 唐小卿 | Endogenous hydrogen sulfide is involved in asymmetric dimethylarginine-induced protection against neurotoxicity of 1-methyl-4-phenyl-pyridinium Ion | Neurochem Res | 2011 |
14 | 田绍文 | Nicotine enhances contextual fear memory reconsolidation in rats. | Neuroscience Letters | 2011 |
15 | 田绍文 | Ventrolateral prefrontal cortex is required for fear extinction in a modified delay conditioning paradigm in rats | Neuroscience | 2011 |
16 | 欧阳新平/田绍文* | Rapid eye movement sleep deprivation disrupts context-modulated effects on morphine locomotor sensitization in mice | Neuroscience Letters | 2011 |
17 | 凌宏艳 | MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling | Clin Exp Pharmacol Physiol. | 2011 |
18 | 周寿红 | Subtoxicdose of chlorpyrifos down regulates ABCA1 expression and accelerates formation of atherosclerosis Induced by the high fat diet inNew Zealandrabbits | Prog Biochem Biophys. | 2011 |
19 | 顾洪丰 | Curcumin alleviates neuropathic pain through decreasing the expressions of proinflammatory cytokines produced by TLR4 pathway in the spinal cord of rats | Prog Biochem Biophys. | 2011 |
20 | 唐小卿 | Neuroprotective effect of asymmetric dimethylarginine against 1-methyl-4-phenylpyridinium ion-induced damage in PC12 cells | Clin Exp Pharmacol Physiol. | 2010 |
21 | 唐小卿 | Hydrogen sulfide antagonizes homocysteine-induced neurotoxicity in PC12 cells | Neuroscience Research | 2010 |
22 | 唐小卿* | Daxx mediates oxidized low density lipoprotein induced cholesterol accumulation and apoptosis in macrophages by upregulating caveolin expression | Prog Biochem Biophys. | 2010 |
23 | 田绍文 | Antidepressant- and anxiolytic effects of the novel melatonin agonist Neu-P11 inrodent models | Acta Pharmacologica Sinica | 2010 |
24 | 周寿红 | Paraoxon attenuates vascular smooth muscle contraction through inhibiting Ca2+ influx in the rabbit thoracic aorta | J Biomed Biotechnol. | 2010 |
25 | 周寿红 | Paraoxon down regulates ATP-binding cassette transporter A1 expression and decreases cholesterol efflux through cyclic AMP signaling pathway in RAW 264.7 macrophage-derived foam cells | Prog Biochem Biophys. | 2010 |
26 | 尹蔚兰/ 唐小卿* | Hydrogen sulfide inhibits MPP+-induced apoptosis in PC12 cells | Life Sciences | 2009 |
27 | 田绍文 | Rapid eye movement sleep deprivation does not affect fear memory reconsolidation in rats, | Neuroscience Letters | 2009 |
28 | 凌宏艳 | Changes in microRNA profile and effects of miR-320 ininsulin-resistant 3T3-L1 adipocytes | Clin Exp Pharmacol Physiol. | 2009 |
29 | 顾洪丰 | Effect of inhibition of toll like receptor 4 on the development of atherosclerosis in apolipoprotein E knockout (apoE-/-) mice | Prog Biochem Biophys. | 2009 |
30 | 顾洪丰 | Effects of chronic mild stress on the development of atherosclerosis and expression of toll-like receptor 4 signaling pathway in adolescent apolipoprotein E knockout mice. | J Biomed Biotechnol. | 2009 |
31 | 唐小卿 | Effect of hydrogen sulphide on beta-amyloid-induced damage in PC12 cells. | Clin Exp Pharmacol Physiol. | 2008 |
32 | 顾朝亮/ 田绍文* | Chronic morphine selectively impairs cued fear extinction in rats: Implications for anxiety disorders associated with opiate use. | Neuropsychopharmacology | 2008 |
33 | 田绍文 | Prior chronic nicotine impairs cued fear extinction but enhances contextual fear conditioning in rats | Neuroscience | 2008 |
34 | 凌宏艳/ 胡 弼* | Effects of rosiglitazone on the proliferation of vascular smooth muscle cell induced by high glucose | Cardiovasc Drugs Ther | 2008 |
35 | 顾洪丰 | Effects of (-)-epigallocatechin-3-gallate on the development of atherosclerosis and toll-like receptor 4-nuclear factor kappa B signaling pathways in apoE-/- mice. | Cell Biology International | 2008 |
