遗传学——从基因到基因组
科学版研究生教学丛书 | ||||
Hartwell，L.H.(美) 着 | ||||
科学出版社 | 2003年6月出版 | |||
定价：78.00 | 语种：英文 | |||
标準书号：7-03-011098-6 | 装帧：平装 | |||
版本：第一版 影印版 | 开本：大16开 | |||
责任编辑：盖宇 | 字数：1866千字 | |||
读者对象：本科以上文化程度 | 页数：865 | |||
书类：研究生教育类 | 册/包：3 | |||
编辑部： 科学生物分社 | ||||
附注： | ||||
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20世纪大家见证了生物学核心领域遗传学的兴起。鉴定单个基因及其功能后，遗传学研究者逐渐意识到，没有基因是单独作用的，各种生命事件是经由基因和蛋白质网路複杂分子的相互作用。
本书试图集成当代遗传学知识和方法，内容主要包括经典遗传学——基因传递规律；分子遗传学——DNA结构及其如何指导蛋白质合成；基因组学——基因分离新技术和有机体完整基因组深入分析；人类遗传学——基因如何调控健康和疾病状态；生命形式的统一——来自不同有机体的信息合成为一个整体核心；分子进化——物种如何进化和趋异。
本书适用于高等院校生命科学、医药卫生、农林渔牧等专业师生使用，并可供相关专业研究人员阅读参考。
本书试图集成当代遗传学知识和方法，内容主要包括经典遗传学——基因传递规律；分子遗传学——DNA结构及其如何指导蛋白质合成；基因组学——基因分离新技术和有机体完整基因组深入分析；人类遗传学——基因如何调控健康和疾病状态；生命形式的统一——来自不同有机体的信息合成为一个整体核心；分子进化——物种如何进化和趋异。
本书适用于高等院校生命科学、医药卫生、农林渔牧等专业师生使用，并可供相关专业研究人员阅读参考。
目录
About the Autmor
Preface
PROLOGUE
PART Ⅰ Basic Principles:How Traits Are Transmitted
CHAPTER 1 Mendel\'s Breakthrough:Patterns,Particles,and Principles of Heredity
CHAPTER 2 Extensions to Mendel:Complexities in Relating Genotype to Phenotype
CHAPTER 3 The Chromosome Theory of Inheritance
CHAPTER4 Linkage,Recombination,and the Mapping of Genes on Chromosomes
PART Ⅱ What Genes Are and What They Do
CHAPTER 5 DNA:How the Molecule of Heredity Carries,Replicate,and Recombines
CHAPTER 6 Anatomy and Function of a Gene:Dissection Through Mutation
CHAPTER 7 Gene Expression:The Flow of Genetic Information from DNA via RNA to Protein
PART Ⅲ Using Genetic Engineering to Unravel the Information in Genomes
CHAPTER 8 DNA a High Resolution:Use of DNA Cloning,PCR,and Hybridization as the Tools of Genetic Analysis
CHAPTER 9 The Direct Detection of Genotype
CHAPTER 10 The Mapping and Analysis of Genomes
PART Ⅳ How Genes Travel
CHAPTER 11 The Eukaryotic Chromosome:An Organelle for Packaging and Managing DNA
CHAPTER 12 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes
CHAPTER 13 The Prokaryotic Chromosome:Genetic Analysis in Bacteria
CHAPTER 14 The Chromosomes of Organelles Outside the Nucleus Exhibitis NonMendelian Patterns of Inheritance
PART Ⅴ How Genes Are Regulated
CHAPTER 15 Gene Regulation in Prokaryotes
CHAPTER 16 Gene Regulation in Eukaryotes
CHAPTER 17 Cell-Cycle Regulation and the Genetics of Cancer
PART Ⅵ Gene Regulation and Development:Portraits of Model Eukaryotic Organisms
USING GENETICS TO STUDY DEVELOPMENT
An Introduction to the Genetic Portraits
CHAPTER 18 Saccharomyes cerevisiae:A Genetic Portrait of Yeast
CHAPTER 19 Arabidopsis thalinana:Genetic Portrait of a Model Plant
CHAPTER 20 Caenorhabditis elegans:Genetic Portrait of a Simple Multicellular Animal
CHAPTER 21 Drosophila melanogaster:Genetic Portrait of the Fruit Fly
CHAPTER 22 Mus musculus:A Genetic Portrait of the House Mouse
PART Ⅶ How Genes Change
CHAPTER 23 The Genetic Analysis of Populations and How They Evolve
CHAPTER 24 Evolution at the Molecular Level
EPILOGUE Human Genetics and the Future of
APPENDIX A Guidelines for Gene Nomenclature
APPENDIX B Brief Answers Section
GLOSSARY
CREDITS
INDEX
Preface
PROLOGUE
PART Ⅰ Basic Principles:How Traits Are Transmitted
CHAPTER 1 Mendel\'s Breakthrough:Patterns,Particles,and Principles of Heredity
CHAPTER 2 Extensions to Mendel:Complexities in Relating Genotype to Phenotype
CHAPTER 3 The Chromosome Theory of Inheritance
CHAPTER4 Linkage,Recombination,and the Mapping of Genes on Chromosomes
PART Ⅱ What Genes Are and What They Do
CHAPTER 5 DNA:How the Molecule of Heredity Carries,Replicate,and Recombines
CHAPTER 6 Anatomy and Function of a Gene:Dissection Through Mutation
CHAPTER 7 Gene Expression:The Flow of Genetic Information from DNA via RNA to Protein
PART Ⅲ Using Genetic Engineering to Unravel the Information in Genomes
CHAPTER 8 DNA a High Resolution:Use of DNA Cloning,PCR,and Hybridization as the Tools of Genetic Analysis
CHAPTER 9 The Direct Detection of Genotype
CHAPTER 10 The Mapping and Analysis of Genomes
PART Ⅳ How Genes Travel
CHAPTER 11 The Eukaryotic Chromosome:An Organelle for Packaging and Managing DNA
CHAPTER 12 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes
CHAPTER 13 The Prokaryotic Chromosome:Genetic Analysis in Bacteria
CHAPTER 14 The Chromosomes of Organelles Outside the Nucleus Exhibitis NonMendelian Patterns of Inheritance
PART Ⅴ How Genes Are Regulated
CHAPTER 15 Gene Regulation in Prokaryotes
CHAPTER 16 Gene Regulation in Eukaryotes
CHAPTER 17 Cell-Cycle Regulation and the Genetics of Cancer
PART Ⅵ Gene Regulation and Development:Portraits of Model Eukaryotic Organisms
USING GENETICS TO STUDY DEVELOPMENT
An Introduction to the Genetic Portraits
CHAPTER 18 Saccharomyes cerevisiae:A Genetic Portrait of Yeast
CHAPTER 19 Arabidopsis thalinana:Genetic Portrait of a Model Plant
CHAPTER 20 Caenorhabditis elegans:Genetic Portrait of a Simple Multicellular Animal
CHAPTER 21 Drosophila melanogaster:Genetic Portrait of the Fruit Fly
CHAPTER 22 Mus musculus:A Genetic Portrait of the House Mouse
PART Ⅶ How Genes Change
CHAPTER 23 The Genetic Analysis of Populations and How They Evolve
CHAPTER 24 Evolution at the Molecular Level
EPILOGUE Human Genetics and the Future of
APPENDIX A Guidelines for Gene Nomenclature
APPENDIX B Brief Answers Section
GLOSSARY
CREDITS
INDEX
